Timberland Is Investing Further in Regenerative Agriculture

Timberland Is Investing Further in Regenerative Agriculture

When I very first started out writing in January of 2019 about regenerative agriculture — a type of farming that focuses on soil health — it was tough to locate mentions of this expression, which was by now gaining prominence in the food items house, any where in manner publications. But the momentum’s been escalating steadily considering the fact that then and the dialogue has far too, as firms like Patagonia, Eileen Fisher and Kering devote in this variety of agriculture that is increasingly being considered as an critical component of any sustainable source chain.

Resource website link

Prostate Cancer Drug Could Be ‘Game Changing’

Prostate Cancer Drug Could Be 'Game Changing'


FRIDAY, May possibly 29, 2020 (HealthDay Information) — For guys with sophisticated prostate most cancers, a new hormone remedy pill is effective much better than normal injections — and carries a substantially decrease chance of heart attack or stroke, a scientific trial has discovered.


The drug, termed relugolix, is not but permitted by the U.S. Food and Drug Administration. If it gets the inexperienced light, on the other hand, it would be “sport-changing,” mentioned Dr. Neal Shore, lead researcher on the trial.


Hormone remedy has long been a regular treatment for superior prostate most cancers — which include conditions the place the tumor has distribute past the prostate gland or recurred following procedure with surgical procedure or radiation.


The objective is to suppress androgen hormones, including testosterone, mainly because they gas the progress of prostate tumors.


Correct now, that’s generally performed with injection drugs referred to as LHRH agonists. The trouble is that the prescription drugs originally trigger a surge in testosterone, in advance of dramatically slicing stages of the hormone. That surge can cause cancer-linked symptoms, this kind of as bone pain and urinary complications, to flare.


“It truly is like possessing a race and telling folks to to start with take 10 ways back, and then get started running,” said Shore, medical director of the Carolina Urologic Study Heart in Myrtle Beach, S.C.


In contrast, relugolix — taken as a everyday pill — fast lowers testosterone levels, the demo found.


Even much more importantly, Shore reported, it had a reduced threat of cardiovascular “occasions” — outlined as a heart attack, stroke or demise from any trigger.


Above 48 weeks, that risk was 54% lower between guys specified relugolix, as opposed to a standard LHRH agonist termed leuprolide.


“That is pretty substantial,” explained Dr. William Cance, chief health care and scientific officer for the American Cancer Culture.


“This drug quite significantly checks all the bins,” claimed Cance, who was not involved in the study.


Additional exploration is wanted on the medication’s lengthy-term efficiency, he observed. But if it can be permitted, Cance stated, it would very likely be favored about LHRH agonists.


The conclusions are being released in the New England Journal of Medicine (NEJM), and concurrently documented Friday at the virtual once-a-year meeting of the American Culture of Scientific Oncology.


Source website link

How to keep your rental car clean


How to keep your rental car clean

Are you planning your vacation in Santorini Santorini car rental and you are sceptical about renting a car? We know that sometimes a rental car is a huge responsibility and it might get you anxious but we have created a list of things that will help you keep your rental car clean.

If you have booked your vacation and you have second thoughts about the rental cars, do not worry. Our tips on how to keep your rental car clean will come to your rescue . If you will follow them you are going to drop off a spotless car which will look brand new.


1. Never eat or drink in the car

This one is quite obvious but we think that some people still need to be reminded about it. When you rent a car, they usually come right after a car wash. Some companies even vacuum, power wash and disinfect their cars with steam machines for hygiene reasons .

It is a pity to make your rental car dirty since the first day that you will have it delivered all because you wanted to eat Greek gyros and drink sodas in the car. In Santorini there are a lot of nice places to eat and there are a lot of choices. From Greek gyros and fresh fish to more gourmet dishes with extraordinary sides and wine.

You can find a variety of restaurants where you can sit and dine in, saving your rental car from a massive spil or sauce stain which will probably cost you more money when you drop it off.

2. If you have kids, organize your trip in a smart way

We know that travelling with kids can get a little messy sometimes. If your kids are young enough and hey cannot obey rules such as “do not spill your juice in the car” or “we can not colour with markers in the car”, there are alternatives. We have some propositions for you below.

You can use a plastic box to keep all the juice bottles and snacks so that they are not all over the car seats. You can get one for a ridiculous price at any local supermarket. You can also organise some other activities so that you will be able to avoid markers that can ruin the inside of the car.

A smart tip is to ask for a rental car with dark-coloured seats so that if you will have an accident it will be easier to clean up or even hide it if it is not completely cleaned. Please remember to keep their shoes off the car seats as it is neither sanitary or nice as a type of behaviour.

3. If you can not avoid food in the car, there are solutions

When you are travelling in Santorini with your children there is probably no way that you will avoid food in the car. They will get hungry as soon as you leave your hotel and get in the car, we know your struggles. There are some ways that you can make your road trips spill-free.

You can opt for snacks that are not juicy, have sauces or bright coloured fruit that can stain fabrics. The last thing you need is a grey car seat to be stained by a strawberry! You can choose fruit that do not require peeling  like a banana and snacks that are not going to get everywhere like a toast with only cheese.

Furthermore, you could just make a stop and eat out of the car if your road trip is longer than 2 hours. Of course you can drink water or any soda that cannot stain fabrics or you could simply use straws and spill-free cups.

4. Towels to the rescue

When visiting the beaches in Santorini you know that sand will get EVERYWHERE. It is a trait of the beaches there. No matter how many times you will get your feet washed, sand will manage to get in the rental car. If you will stay for many days, your car will look like it has been through a sandstorm by the time your vacation is over.


Let alone the water or sweat stains that can be left on a car seat. If you have gotten into your car right after visiting a beach, you might have noticed a white water mark on your seats. It is not difficult to remove as it is just salt water but when it comes to a rental car, you simply do not have the means to clean it as you are on vacation.

You can avoid that -at least until a certain point- by using towels. Pack an extra towel per person so that you can put it on your seat. This way you will limit the sand and the water stains on the seats of your rented car.

5. Cleaning kit

If you are a cleaning freak and you are sure that you are going to need to clean your rental car just because you feel like it, prepare a cleaning kit. Go to a local super market and get a carpet cleaner, a microfibre duster and a wind shield cleaner and you have a DIY cleaning kit.

You can also ask the car rental company for one as they might offer it to clients who rent a car for a longer time.

6. Keep a bottle of water in the trunk

As far as the sand or dirt on your feet and hands after a visit at the beach, there is a simple yet effective solution. You can keep a water bottle in your trunk so that you can clean your children’s feet (and your own of course) after your swim sessions. You can either dry them with a towel or wait a few minutes for the sun and the heat to dry them off for you.

7. Know when and if you need a car wash

If you are going to be careful and follow the tips mentioned above, you will probably not need to get the car in a car wash. Of course it is completely up to you and you can do it if you wish to.It is kind of a common sense thing though, as if you have stained the car or if the outside is too dirty or muddy, you might have to clean it up before delivering it back to the car rental company.


You can also ask the car rental company if they require a car wash, or read the contract to make sure if you need to return it cleaned or not.

Overview on how to keep your rental car clean

If you are going to follow our tips on how to keep your rental car clean, we are certain that you will not face any problems with the car rental company. You will enjoy your trip and at the same time save money as you will not have to pay to have your car cleaned.

See more about Santorini Rent a Car

Who What Wear Spotlight: How We’re Helping Small Businesses

Who What Wear Spotlight: How We're Helping Small Businesses

Who What Don Spotlight was born when our co-founder Katherine Electric power experienced the plan to use some of our advertisement inventory to assist smaller vogue and natural beauty enterprises that have been impacted by COVID-19. Starting from Monday 25th May, every week we will convert the highlight on a corporation that will get a complimentary 7 days-long exposure package showcasing the enterprise, which includes an editorial story on WhoWhatWear.co.united kingdom, social advertising and ads on the website top to the written content. 

With these endeavours, we are extending a hand to the style-and-magnificence group, applying our advertisement stock for superior, and directing our audience of 16+ million shoppers globally to the brands that have to have their assistance the most. Our audience still wants to store and see the very best new manufacturers and cares additional than at any time about who they are picking out to aid with their buys, so this is a win-get for both of those the founders of these companies and our neighborhood. Who What Don would not be where we are without assistance from our field, and we’re incredibly fired up to give anything good again with this initiative, specifically to people who are underrepresented.

If you’d like to apply for your organization or know a compact fashion or beauty small business that would be fantastic for this, our application form is open—here is exactly where to apply for the British isles website (and for American companies here is the application variety for the US plan). Our hope is to continue to evolve this plan, working with it as a devoted franchise to support scaled-down companies.

Below is the form to use for the WWW British isles Spotlight application. 

Source link

FDA Test Warning, ‘Warp Speed’ Vaccine Project

FDA Test Warning, 'Warp Speed' Vaccine Project


What your doctor is looking through on Medscape.com:&#13


May perhaps 15, 2020 — Here are the coronavirus stories Medscape’s editors all around the globe think you require to know about now: 


Food and drug administration Warning on Precision of Abbott ID NOW Quick Take a look at&#13


Preliminary knowledge propose that Abbott Labs’ ID NOW immediate take a look at for COVID-19, reportedly in use to screen White Property team, may possibly give phony-negative outcomes, the US Meals and Drug Administration (Fda) said in an inform late Thursday.


To day, the Fda has acquired 15 adverse celebration stories about the Abbott ID NOW examination that advise some customers are receiving inaccurate negative success, the company said, and some scientific tests have recognized accuracy issues with the exam. The agency is investigating no matter whether this could be due to the sorts of swabs or viral transportation media utilised.


“This check can nevertheless be employed and can the right way establish many constructive instances in minutes. Detrimental benefits might need to have to be confirmed with a significant-sensitivity licensed molecular test,” an Fda formal explained in the notify assertion.


Particulars on ‘Operation Warp Speed’ Vaccine Challenge&#13


Less than an initiative called “Procedure Warp Pace,” a group of federal officers, scientists, and drug providers have the problem of acquiring a coronavirus vaccine by the close of the 12 months.


The workforce contains leaders from the Centers for Ailment Handle and Prevention, the Fda, the Countrywide Institutes of Overall health, the Section of Wellbeing and Human Companies (HHS), and the Division of Protection. President Donald Trump discussed details of the initiative during a push briefing Friday afternoon. 


Public health and fitness gurus have predicted that a coronavirus vaccine could choose 12 to 24 months to deliver. Operation Warp Speed’s target is to minimize that timeline by concurrently planning the production and distribution procedures so drug organizations can fill vaccine vials at the time the system is all set. Less than the directive, orders were being positioned this week for vaccine-associated supplies like glass vials, needles, and syringes, reported Alex Azar, HHS Secretary.


Keep-at-Dwelling Orders Correlated With Slower Spread&#13


Two reports recommend that authorities stay-at-dwelling orders have had a sizeable effect on slowing the unfold of COVID-19. A person located a considerable big difference in the progress of COVID-19 situations involving border counties in Illinois, which has a remain-at-house buy, and Iowa, which does not. A different calculated how much shelter-in-place orders have lowered the distribute of the virus compared with other social distancing measures. 


Source hyperlink

Upscale Lifestyle Brand Is Hiring A Virtual E-Commerce Assistant (Remote)

Upscale Lifestyle Brand Is Hiring A Virtual E-Commerce Assistant (Remote)

Upscale, life-style brand name seeks Remote E-commerce Assistant. The position sits on a motivated Merchandising & Profits team. This popular Usa brand sells to e-commerce manufacturers and other on-line channels.

​Bring your e-commerce working experience or powerful administrative skills and wish to mature on an E-Commerce crew as an on-line Merchandiser, Web Merchant or inside of a dynamic Gross sales or Internet marketing team in the vogue marketplace! Ought to be comfortable operating from dwelling and using on the net course from Administrators and cross-teams. This is a direct seek the services of, entire time role, distant, functioning inside of the PST zone (Los Angeles, CA).


  • Potential to discover techniques swiftly, and make correct pricing changes, SKUs, design and style updates, and so on., as essential
  • Load and post customer e-commerce orders even though retaining product prepared dates and availability by means of the process
  • Update SKU and pricing, item descriptions for catalog or website merchandising
  • Operate Gross sales stories and handle inventory amounts within the system
  • Ability to study and take guidelines and keep shopper details for products orders and Showroom shows by way of email or mobile phone
  • Pull products and fashion clothing online and offline for Buyer meetings and consumer shows
  • Organize and acquire conference notes, create and sustain Profits calendars and deadlines and other similar office assignments


  • Will have to have a minimum amount of 2-5 decades of knowledge (or a lot more) as a product sales assistant, on the web client assistance, e-commerce, wholesale admin, or account rep practical experience. Powerful MS office abilities would operate very well in this purpose.
  • Have to have stable Excel competencies to operate and update Profits & Merchandising reports, weekly information reports, account facts, stock updates, and item delivery reviews
  • Encounter with CRM, EDI or other inventory programs is highly favored
  • Prior interface & electronic mail communications with Revenue Reps, on the internet Retailers, Consumers or experience as a Gross sales Assistant (or Wholesale CSR) is chosen
  • Encounter doing work below modifying seasonal timelines is extremely preferred.
  • Comprehension of attire lines, collections, retail & wholesale production is preferred
  • Google analytics knowledge or desire to study along with on line Merchandising
  • A handy, crew player would be appreciated… and “arranged” is your center identify!
  • This is a comprehensive-time virtual part. Will have to be determined and equipped to do the job independently from household.
  • Capacity to keep on being distant indefinitely, with a want to grow within just a potent and thriving e-comm manner staff

This is a direct employ, complete-time function distant with working several hours in PST zone. Several hours are comprehensive time through conventional business hours Monday via Friday. Potential overtime primarily based on job deadlines.

Resource connection

Celebs Love L’Oréal Paradise Mascara, and It’s Only £12

Celebs Love L'Oréal Paradise Mascara, and It's Only £12

So, when it introduced in the United kingdom nearly 3 several years in the past, it is pointless to say that individuals flocked to the aisles of Boots to inventory up – which includes me. And, unlike what comes about with so several United kingdom make-up launches, the fuss about Paradise under no circumstances did seriously die down. Three years on, and it is still a everlasting element in my makeup routine. With just 1 coat, lashes surface considerably fuller and extended, but retain a weightless really feel that is each relaxed and mess-absolutely free. Not only that, but soon after many hrs of don, even with my oil-vulnerable lids, it fails to smudge (buddies have observed that this is not essentially the circumstance for them so they choose for the water-resistant system as an alternative, which looks to do the trick).

If I could only continue to keep keep of 1 mascara in my fairly shamefully significant collection, I would not even hesitate in deciding on this a single. When compared to other far far more high-priced solutions, I can categorically say that L’Oréal Paris Paradise Volumising Mascara is just about a single of the most volumising and lengthening that dollars can obtain. Never imagine me? Just ask Beyoncé.

Supply connection

Stroke in Young Adults, Test Safety Issues

Stroke in Young Adults, Test Safety Issues

What your doctor is reading on Medscape.com:

APRIL 25, 2020 — Here are the coronavirus stories Medscape’s editors around the globe think you need to know about today: 

Stroke in Young Adults

Investigators from Mount Sinai Health System in New York City report five cases of large-vessel stroke over a 2-week period in COVID-19 patients under age 50 years — a sevenfold increase over the norm.

The cases, which involved only mild or no COVID-19 symptoms, are described in a rapid communication to be published online April 29 in the New England Journal of Medicine.

“It’s been surprising to learn that the virus appears to cause disease through a process of blood clotting,” lead investigator Thomas Oxley, MD, PhD, told Medscape Medical Newsadding that the message for neurologists and other physicians is “we’re learning that this can disproportionally affect large vessels more than small vessels in terms of presentation of stroke.”

Abbott Test Safety Issues?

Lab workers at Abbott Laboratories are raising alarm bells about the safety of a widely distributed rapid coronavirus test touted repeatedly by President Donald Trump. They are concerned in particular about the risk of infection of those handling the test, saying the test requires more than the usual protection for those who administer it.

Kaiser Health News reports on this and other “hiccups” with respect to the test, as well as plans to develop safety recommendations to address the issues.

Bud Rose

Burton “Bud” Rose, MD, renowned kidney specialist, entrepreneur, and creator of the popular online medical education resource UpToDate, died Friday from complications of COVID-19 at age 77. You can read more about his achievements and invaluable contributions in this moving tribute to “the Steve Jobs of medicine” on Stat News.

VTE vs Bleeding Risk

Clinicians have been sounding the alarm about unusually high rates of thrombosis among COVID-19 patients, and news this week that Broadway star Nick Cordera had one of his legs amputated as a result of thrombotic complications of COVID-19 brought the issue center stage.

Now a panel of 36 international experts has published a report summarizing the evidence on the thrombotic disease pathogenesis, diagnosis, and management in patients with COVID-19 as well as the management of thrombotic disease in patients without COVID-19. The panel also addresses concerns about balancing the need for thromboprophylaxis against the risk for bleeding.


“There’s so much confusion, so much heterogeneity in the way people are practicing — and granted, the evidence is not perfect — but I thought it’s about time to provide a thorough assessment of the known literature but also some consensus-based recommendations,” Behnood Bikdeli, MD, New York–Presbyterian Hospital/Columbia University Irving Medical Center and Yale University’s Center for Outcomes Research and Evaluation, New Haven, Connecticut told theheart.org | Medscape Cardiology.

Immunity Passports?

As part of efforts to enable people to travel or return to work, some governments have floated the idea of providing “immunity passports” indicating an individual is COVID-19 risk-free.

Not so fast, says the World Health Organization (WHO), which has published guidance on adjusting public health and social measures for the next phase of the pandemic response. The WHO states there is currently no evidence that people who have recovered from COVID-19 and have antibodies are protected from a subsequent infection.

In a scientific brief published online April 24, the WHO states that study on this matter is ongoing, but at this point evidence is lacking about the effectiveness of antibody-mediated immunity to ensure that an individual is risk-free, and that the use of such classifications could increase the risks of continued virus transmission.


The United States will have no official role in a new WHO initiative involving several world leaders and designed to accelerate the development of tests, drugs, and vaccines against the coronavirus.

The Access to COVID-19 Tools Accelerator initiative, a “landmark collaboration” that aims to speed tool development and ensure equal access worldwide, was announced Friday in the wake of a decision by President Trump to suspend US contributions to the global health body, as reported by The Hill. A spokesman for the US mission in Geneva said there will be no official US participation.

Managing Hypoxia

In hypoxic patients with COVID-19 and an indication for endotracheal intubation, an airway expert should perform intubation, an N-95/FFP-2 or equivalent respirator mask should be used, and other PPE and infection control precautions should be taken, according to new guidelines from the Society of Critical Care Medicine and the European Society of Intensive Care Medicine.


Staff presence in the room should be minimized and use of videolaryngoscopy should be considered if available, the authors note.

Medscape Drugs and Diseases has provided a quick summary of the guidelines, which also address patients in whom endotracheal intubation is not indicated and who are not tolerating supplemental oxygen or high-flow nasal cannula use.

In Memoriam

As frontline healthcare workers care for patients with COVID-19, they commit themselves to difficult, draining work and put themselves at risk of infection. More than 500 throughout the world have died. 

Medscape has published a memorial list to commemorate them. We will continue updating this list as, sadly, needed. Please help us ensure this list is complete by submitting names with an age, profession or specialty, and location through this form. 

Medscape Medical News

© 2020 WebMD, LLC. All rights reserved.

Source link

Saliva COVID Test Alternative to Deep Nasal Swab

Saliva COVID Test Alternative to Deep Nasal Swab

By Dennis Thompson

HealthDay Reporter

MONDAY, April 27, 2020 (HealthDay News) — Testing for the COVID-19 coronavirus can be an unpleasant affair, with a doctor or nurse shoving a cotton swab deep into your nasal cavity to get a good sample.

But results that are just as accurate can be obtained from a more easily acquired saliva sample, a new Yale study reports.

Saliva samples taken from just inside the mouth were more accurate and consistent than deep nasal swabs taken from 44 patients and 98 health care workers, the researchers reported.

For instance, saliva samples detected the coronavirus in two health care workers without symptoms who’d previously been cleared by a deep nasal swab, the Yale researchers said.

“We found it performs as well as, and in a number of cases better, than the nasopharyngeal swab,” said lead researcher Anne Wyllie, an associate research scientist at the Yale School of Public Health in New Haven, Conn. “We have another very viable option.”

The findings were published April 22 on medRxiv, a preprint server for emerging research.

Switching to saliva testing would have many advantages over taking deep nasal samples, Wyllie said.

Saliva testing requires far fewer materials, and thus would be more immune to the supply chain problems that have hampered efforts to expand COVID-19 testing through deep nasal swabs, Wyllie said.

“There wouldn’t be a shortage of things to collect the saliva sample in, because there are so many options that are possible,” Wyllie said, adding that any collection cup or container could be reused after it’s been disinfected.

Health care workers also would need to wear less personal protective equipment when taking a saliva sample compared with a nasopharyngeal swab, Wyllie said.

Nasopharyngeal testing involves inserting a swab deep into the nose, into the region of the pharynx. The swab is then rotated to collect secretion before it’s yanked out and sent off to a lab.

“Taking the swab itself can cause patients to sneeze or cough, which carries a lot of risk to the health care workers,” Wyllie said.


Saliva tests also could be easily adapted for rapid home testing, Wyllie added, noting that most people would be hard-pressed to shove a swab deep enough into their own noses to get a good sample.

“I can’t imagine reliably doing that to myself,” Wyllie said of performing a self-swab.

The U.S. Food and Drug Administration gave emergency use authorization on April 13 for a saliva-based test for COVID-19 developed by researchers at RUCDR Infinite Biologics, a Rutgers University-backed group. The approved test must be conducted in a health care setting under supervision of a qualified professional.

Wyllie noted that a number of other research teams are also testing the reliability and accuracy of saliva testing, and coming up with good results.

Some places already are moving toward saliva testing.

Jill Taylor, director of the New York State Public Health Department’s Wadsworth Center, said her institution might switch to a combined light nasal swab and saliva test instead of deep nasopharyngeal swabbing, based on an in-house study they conducted.

A swab run around the inside of the nose combined with a saliva test would only miss 5% of positive COVID-19 cases, compared with 2% missed by nasopharyngeal swab testing, the New York researchers found in a study of 226 specimens.

“The [nasopharyngeal] swab was clearly the best sample, but the nasal swab and saliva were quite good also,” Taylor said. “So, at the moment we are looking at combining a nasal swab and saliva so that compared to the nasopharyngeal we would be close to the sensitivity.”

Wyllie believes that saliva testing will become the standard for COVID-19 testing in the future, particularly given the need for quick testing as the United States and other nations start to emerge from lockdown.

“It’s going to take a lot of pressure off different aspects of supply chains. It’s going to be so much quicker and easier to get saliva samples. I really think this is going to be the way forward,” Wyllie said.

WebMD News from HealthDay


SOURCES: Anne Wyllie, Ph.D., associate research scientist, Yale School of Public Health, New Haven, Conn.; Jill Taylor, Ph.D., director,  Wadsworth Center, New York State Public Health Department; April 22, 2020, medRxiv, online

Copyright © 2013-2020 HealthDay. All rights reserved.

Source link

Carine Roitfeld Is Organizing a Virtual Fashion Show With Virgil Abloh, Hailey Bieber, Marc Jacobs and More

Carine Roitfeld Is Organizing a Virtual Fashion Show With Virgil Abloh, Hailey Bieber, Marc Jacobs and More

Virgil Abloh and Hailey Bieber.

When manner folks listen to “amfAR,” they might consider of models carrying couture at Cannes, and for fantastic cause: The basis commonly depends on gorgeous persons wearing fancy frocks to increase income for the AIDS/HIV research it conducts. But with gatherings on the crimson carpet and in far-flung locales like the French Riviera off the table and Covid-19 dominating the discussion, amfAR is pivoting: to coronavirus study, and to a distinct form of style advocacy. 

On May well 1, a “virtual runway” established by Carine Roitfeld and hosted by Derek Blasberg will stream on YouTube to “raise awareness for investigation initiatives led by the amfAR Fund to Combat Covid-19,” according to a press release. The 30-minute electronic occasion, which is also serving as the second-ever CR Runway, will deliver with each other some of fashion’s most significant names to share “walks and words and phrases” in what the organizers hope will consequence in “a instant of artistic inspiration and uplifting amusement.”

Resource link